The scheme (pictured above) will provide a range of new homes and commercial space with a GDV of approximately £230m.
The development will replace an existing multi-let office building and include 332 apartments, of which 71 will be affordable.
It will also provide approximately 10,000 sq ft of mixed B1, D1, A1 and A3 commercial space.
Nick Crawford, managing director at LBS Properties, said: “We are delighted to have received planning permission for this significant development that will provide high-quality new homes, commercial space and extensive public realm, contributing to the evolution of the South Quay area as an attractive place to live and work.
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“It will combine with the Madison – due to complete in 2020 – to provide a new public square for Marsh Wall East, and over 750 new homes in two slender towers.”
The project was recommended for approval by LB Tower Hamlets planning officers in 2017, but was initially refused by elected members of the strategic development committee.
However, a public inquiry was held in September 2018, with planning permission granted this month.
The planning inspectorate report stated: “The building has been designed to an exemplary standard, making a significant new place and improving the quality of the Isle of Dogs cluster.
“A built development of this quality, seen in conjunction with the Madison tower ‘bookending’ a public park, would create an identifiably distinct place, making a major contribution to the character and quality of the Marsh Wall street scene.”
The project has been designed by Make Architects, with Forsters LLP and Russell Harris QC acting for the applicant Cubitt Property Holdings Limited.